Sven will visit the Center for Information and Neural Networks (CiNet) to talk about "High-precision neurophysiology of (natural) human movement" at the UK-Japan Pain workshop, in Osaka, Japan
http://www.bestmannlab.com/images/uploads/poster.pdf
We had a great day at the UCL World Stroke day, with lots of empowering and motivating stories shared and conversations started.
Catharina has started her post-doc with wardlab and us, funded by a grant from Brain Research UK. She will work on neurophysiological biomarkers for upper limb recovery in acute stroke patients
Welcome to Lydia Mardell who has started her PhD with us, jointly supervised with Prof Nick Ward. Lydia will work on the neurophysiology of recovery in subacute stroke, using novel MEG approaches
Our paper "Learning from the past and expecting the future in Parkinsonism: Dopaminergic influence on predictions about the timing of future events" by Alessandro Tomassini, Thomas Pollak, Mark Edwards and Sven Bestmann is now in press in Neuropsychologia
https://tmscourses.nl/
Lydia has joined the lab for her PhD rotation project
"Forget-me-some: General versus special purpose models in a hierarchical probabilistic task" - our new paper by Broker, Marshall, Bestmann & Dayan is now published in PLoS One
Our new paper "Computing value from quality and quantity in human decision making" by de Berker, Kurth-Nelson, Rutledge, Bestmann & Dolan is now published in J Neurosci
New paper "Motor training modulates intracortical inhibitory dynamics in motor cortex during movement preparation" by Josh Hadwen, Sven Bestmann & Charlie Stagg is now in press in Brain Stimulation
Sven talks about the role of sensorimotor beta activity at the Analysis & Synthesis of Human/Artificial Cognition and Behaviour workshop at OIST, Okinawa, Japan
Will is funded by an NIH-UCL PhD fellowship over 4 years. Wellcome!
Sven will speak about neurorehabilitation and neuroimaging at the 'Neurorrehabilitación: Atención al daño cerebral y medular adquirido' meeting, Madrid Spain
Our paper "General versus Special Purpose Models in a Hierarchical Probabilistic Task" by Broker F, Marshall LM, Bestmann S, Dayan P is now in press in PLoS One
"Lamina-specific cortical dynamics in human visual and sensorimotor cortices" by Bonaiuto J, Meyer SS, Little S, Rossiter H, Callaghan MF, Dick F, Barnes GR, Bestmann S is now in press in eLife
Sven is chairing the BrainBox Conference 2018, at the Wellcome Collection, sponsored by Rogue Resolutions
Our paper "Computing value from quality and quantity in human decision making" by Archy de Berker, Zeb Kurth-Nelson, Robb Rutledge, Sven Bestmann, and Raymond Dolan, has been accepted in the Journal of Neuroscience
Sven will give two talks and chair two sessions at the 2018 New York City Neuromodulation conference
Our chapter "Preparation of Movement", written with Adrian Heath, is now in press in the new 6th edition of "Cognitive Neurosciences" by Editors David Poeppel, George Mangun, Michael Gazzaniga
Sven will join a panel discussion "Citizens and science advice - challenges and opportunities of participatory science advice" at the EuroScience Open Forum 2018 in Toulouse
New paper accepted in NeuroImage: "Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function", by Tierney T, Holmes N, Meyer S, Boto E, Roberts G, Leggett J, Buck S, Duque-Muñoz L, Litvak V, Bestmann S, Baldeweg T, Bowtell, Brookes MJ, Barnes GR
Carys has joined the lab for a 3 year Post-doc working on brain stimulation and stroke recovery
New paper "Quantifying the performance of MEG source reconstruction using resting state data" by Simon Little, James Bonaiuto, Sofie Meyer, Jose Lopez, Sven Bestmann, Gareth Barnes has been accepted in NeuroImage
Our paper "Age-dependent Pavlovian biases influence motor decision-making" by Chen X, Rutledge R, Brown H, Dolan R, Bestmann, and Galea J has been accepted in PLoS Computational Biology. Great collaboration with the Galealab
Our paper "Pharmacological dopamine manipulation does not alter reward-based improvements in memory retention during a visuomotor adaptation task" by Quattrocchi, Monaco, Ho, Irmen, Strube, Ruge, Bestmann and Galea has been accepted in eNeuro, in collaboration with Galea Lab
Jenny will look at the critical window for recovery in acute and chronic stroke patients with upper limb impairment, funded by a Brain Research UK grant
New paper "Neurodynamic Evidence Supports a Forced-Excursion Model of Decision-Making under Speed/Accuracy Instructions" by Laure Spieser, Carmen Kohl, Bettina Forster, Sven Bestmann, and Kielan Yarrow has been accepted in eNeuro
Our collaborative paper on a new wearable MEG system is now published, thanks to great work with Matthew Brookes' team in Nottingham and Gareth Barnes at the Wellcome Centre for Human Neuroimaging.
Sven will give two lectures at this year's joint meeting of the NYC neuromodulation conference and NANS summer series, in NYC
Sven will present at the Carolina Neurostimulation Conference, in Chapel Hill, USA, organized by Flavio Frohlich and his group
Sven will speak at the opening day of the new MEG centre at Birmingham Psychology
Sven will give the keynote lecture on models and brain stimulation at the Meeting of the minds conference, organized by the Imperial College Neuroscience Society
Our paper "Non-invasive laminar inference with MEG: Comparison of methods and source inversion algorithms" by Bonaiuto J, Rossiter H, Meyer SS, Adams N, Little S, Callaghan M, Dick F, Bestmann S, Barnes G is now in press in NeuroImage
Our Primer on "Transcranial electrical stimulation" with Vincent Walsh is now in press in Current Biology, coming soon
Clarissa has joined the lab to conduct her MSc research project in our lab. Check out her recent Current Biology paper on contagious jawning!
New paper "tDCS changes in motor excitability are specific to orientation of current flow" by Rawiji, Ciocca, Zacharia, Soares, Truong, Bikson, Rothwell, & Bestmann is now in press in Brain Stimulation.
Welcome to both Eve and Haya who will work on brain stimulation approaches to motor learning and rehabilitation
Sven will talk about models and brain stimulation at the student-led BrainDiSC conference at the Bernstein Centre, Freiburg, Germany
Great achievement for Isabella to get a distinction, including her MSc thesis on tDCS and perceptual learning done in our lab...Congrats!
Come to our meeting: BrainBox Initiative Conference 2017, For Non-Invasive, Multimodal, Brain Stimulation and Brain Imaging, 21 - 22 September 2017
Royal College of General Practitioners,
With generous support by RogueResolutions
Find the programme here
Can we non-invasively resolve signals from different cortical layers in humans?
Recent computational, anatomical and physiological evidence suggests that feedforward signals tend to originate in supra-granular cortex and be of predominantly high-temporal frequency content (>30 Hz) whereas feedback signals tend to originate in infra-granular cortex and are characterized by slower dynamics (<30Hz). I will demonstrate that using new recording technology, it is now possible to make frequency-specific laminar inferences with magnetoencephalography (MEG) in a spatially localized and time-resolved manner, non-invasively and in vivo. I will describe global and local analyses for making laminar-specific inferences with MEG using parametric and non-parametric measures, and demonstrate their concordance in simulation. I will then present empirical evidence from a predictive action selection task which shows that spatially resolved laminar inferences of human sensorimotor and visual induced activity can be made using MEG, attributing low frequency (<30Hz) activity to infra-granular sources, and high frequency activity (>60Hz) to supra-granular sources. Finally I will discuss potential extensions of this technique to estimate the time course of laminar activity during evoked responses.
Big thanks to Emra Duzel and Hanneke den Ouden for examining Louise, who passed without corrections. Very proud and congratulations
Looking forward to go to Tohoku University in Japan soon, together with Jimmy Bonaiuito, enabled through the UCL Global Engagement Fund, to teach a module on action, decision making and neuroimaging
Our new paper "Non-invasive laminar inference with MEG: Comparison of methods and source inversion algorithms" by Bonaiuto J, Rossiter HE, Meyer SS, Adams N, Little S, Callaghan MF, Dick F, Bestmann S, Barnes GR is now available in BioRxiv
Our new paper on directional tDCS is online as preprint in bioRxiv now: "tDCS changes in motor excitability are specific to orientation of current flow" by Vishal Rawji, Matteo Ciocca, Andre Zacharia, David Soares, Dennis Truong, Marom Bikson, John Rothwell, and Sven Bestmann
Archy will talk about his work at the WTCN brain meeting on April 28th: "Computation and representation in decision making and emotion"
Archy withstood a barrage of question from Tim Behrens and Michael Browing, and passed his Viva successfully!
Our new opinion article "Are current flow models for transcranial electrical stimulation fit for purpose?" on current flow models and their utility is now published in Brain Stimulation.
Ana Saraiva is now a doctor - having passed the grilling questions by her examiners Essi Viding and Bryan Strange
Sven will speak about "'Understanding and predicting the behavioural consequences of brain stimulation with computational neurostimulation" at the Dept Psychology, Dresden University
Our paper "Reward and punishment enhance motor adaptation in stroke" by Quattrocchi, Greenwood, rothwe,, Galea and Bestmann has been accepted for publication in the Journal Neurology, Neurosurgery and Psychiatry
Our paper "Using generative models to make probabilistic statements about hippocampal engagement in MEG" by Sofie Meyer, Holly Rossiter; Matthew Brookes, Mark W Woolrich, Sven Bestmann & Gareth R Barnes is now in press in NeuroImage
"Response repetition biases in human perceptual decisions are explained by activity decay in competitive attractor models" by Jimmy Bonaiuto, Archy de Berker and Sven Bestmann is now in press in eLife
Sven and Jimmy will talk about the spatial resolution of TMS and computational neurostimulation, respectively.
NYC Neuromodulation 2017 will focus on technologies and mechanism for advanced brain stimulation in areas that include transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), transcranial magnetic stimulation (TMS), high-definition transcranial direct current stimulation (HD-tDCS), electroconvulsive therapy (ECT), deep brain stimulation (DBS), and other emerging areas.
's paper "Pharmacological fingerprints of uncertainty" by Marshall M, Mathys C, Ruge D, de Berker A, Dayan P, Stephan KE, Bestmann S was just accepted in PLOS Biology
Our paper "Neural signatures of value comparison in human cingulate cortex during decisions requiring an effort-reward trade-off", with Miriam Klein-Flugge, Steve Kennerely, Karl Friston, and Sven Bestmann, has now been published in the Journal of Neuroscience. Find the open access paper here
Sven will chair the session on "Computational Neurostimulation" at the 2016 6th International Conference on Transcranial Brain Stimulation, and speak about the use of biophysical models and tDCS
Our paper "Cerebellar tDCS Dissociates the Timing of Perceptual Decisions from Perceptual Change in Speech", by Lametti D, Oostwoud Wijdenes L, Bonaiuto J, Bestmann S, Rothwell JC is now in press in the Journal of Neurophysiology
Sven has presented our work on Computational Neurostimulation at the Centre for Information and Neural Networks, Osaka, Japan.
Archy's paper "Acute stress selectively impairs learning to act", with Margot Tirole, Robb Rutledge, Gemma Cross, Ray Dolan, and Sven Bestmann, is now in press in Nature Scientific Reports
Our paper "Neural signatures of value comparison in human cingulate cortex during decisions requiring an effort-reward trade-off" by Miriam Klein-Flügge, Steve Kennerley, Karl Friston, and Sven Bestmann is now in press in the Journal of Neuroscience
Sven will visit Bryan Strange's StrangeLab at the Centre for Biomedical Technology in Madrid, to talk about our work on high precision MEG using head casts.
Looking forward to our first online seminar, to Leo Cohen's group at NIH, on "Computational Neurostimulation in basic and translational neuroscience"
Sven will talk about "Using TMS to study the transformation from decisions to actions" in the Symposium on "Transcranial Magnetic Stimulation (TMS): a powerful tool for research in psychology and neuroscience", at the ICP in Yokohama, Japan
Sven will speak at Benedetto de Martino's Marr Club in Cambridge, on "Towards a whole brain account of decisions for actions using high precision MEG"
Our paper "Selective alteration of human value decisions with medial frontal tDCS is predicted by changes in attractor dynamics" by Hammerer D, Bonaiuto J, Klein-Flugge M, Bikson M, BEstmann S is now in press in Scientific Reports
Our paper "The Evidence Information Service as a new platform for supporting evidence-based policy: A consultation of UK parliamentarians" by Lawrence N, Chambers J, Morrison S, Bestmann S, O'Grady G, Chambers CD and Kythreotis AP is now in press in Evidence & Policy
Archy's paper "Computations of uncertainty mediate acute stress responses in humans" has been accepted in Nature Communications
Sven and Inge will present their work at the joint UCL - NTT Communication Sciences Laboratories meeting
Our new paper "Causal evidence that intrinsic beta frequency is relevant for enhanced signal propagation in the motor system as shown through rhythmic TMS" by Romei, Bauer, Brooks, Economides, Penny, Thut, Driver, Bestmann, is now i press in NeuroImage
Welcome to Roeland Heerema, Jem Bhatt, and Jeff Inglis, who have joined our lab for their MSc research projects.
http://neuromodec.com/events/updates-in-tdcs-clinical-trials/program/
438.18/AA11: A computational neurostimulation model of the nonlinear effects of tDCS
601.19/L41: A high resolution MEG study of predictive coding in action selection
611.19/Q11: Investigating the effect of current flow on cortical excitability using bipolar tDCS
711.08/V35: Cerebellar tdcs during speech perceptual learning dissociates the act of indicating perception from perceptual change
Sven was elected as new Vice Chair of the Young Academy of Europe at this year's Annual meeting of the YAE
New paper accepted in J Cogn Neurosci, on "The role of Dopamine in temporal uncertainty", by Alessandro Tomassini, Joe Galea, Diane Ruge, Will Penny, Sven Bestmann
as part of the symposium "Investigating Neuronal Computation in Cortical Laminae using Layer-Resolved fMRI & Electrophysiology" at OHBM15, Sven will speak about "Non-invasive electrophysiology of human cortical laminae"
Jimmy's paper "Understanding the nonlinear physiological and behavioral effects of tDCS through computational neurostimulation " by Bonaiuto J, Bestmann S has been accepted in Prog Brain Res, as part of a special volume on "computational neurostimulation"
Rosy will conduct her MSc project with us, on the role of NA on perceptual learning
Louise's work with Paul Bays, "Evidence for optimal integration of visual feature representations across saccades", by Oostwoud Wijdenes L, Marshall L, & Bays PM., has been accepted in the Journal of Neuroscience!
Our paper "Transcranial magnetic stimulation: Decomposing the processes underlying action preparation" by Sven Bestmann and Julie Duque has been accepted for publication in The Neuroscientist
Sven will give the Brain and Cognition Seminar at Neuroscience Centre, University of Geneva
Inge's paper "Testosterone biases the amygdala towards social threat approach" by Radke S, Volman I et al has been accepted in Science Advances
sven will talk about Computational Neurostimulation at the 3rd North America Meeting on Brain Stimulation and Neuroimaging
As part of the symposium on non-invasive brain stimulation, Sven will talk about "Computational Neurostimulation"
Our new open access paper in PLoS Computational Biology can be found here
our paper "Binding space and time through action" by Binetti, Hagura, Fedipe, Tomassini, Walsh, Bestmann has been accepted in Proceedings of the Royal Society B
Sven will present at the symposium "How to use Computational Models to Optimize Brain Stimulation", and Simon at the symposium on "Deep Brain Stimulation", at the 1st International Brain Stimulation Conference, Singapore
Simon has now started his prestigious Wellcome Trust Clinical Training Fellowship with us, and he will work on basic and translational aspects of beta oscillations
Looking forward to be speaking at Trinity College's Institute of Neuroscience on "Are there true Improvements with Neurostimulation?"
Inge has received a prestigious Marie Curie Fellowship to come and work in our lab for two years. Congratulations!
Sven will talk about "How can we bridge between physiological and behavioural effects of tES?" at the NYC Neuromodulation meeting
Miriam's paper "Behavioral Modeling of Human Choices Reveals Dissociable Effects of Physical Effort and Temporal Delay on Reward Devaluation" has been accepted in PLoS CB
Happy new year to all firiends and colleagues!
The list of speakers of the 2015 Magstim Neuroscience Conference in Oxford May 2015, organized by Vince Walsh, Charlie Stagg, and Sven Bestmann
Our paper "The uses and interpretations of the motor-evoked potential for understanding behaviour", by Sven Bestmann and John Krakauer, is now in press in Experimental Brain Research
Sheena has just joined our lab! She also just passed her PhD viva, examined by Heidi Johansen-Berg and Alex Leff.
We're looking forward to Simon joining our lab soon...
We're presenting 7 posters at SfN this year, find us at poster numbers 71.09/GG17, 84.02/NN3, 84.03/NN4, 562.03/UU88, 635.11/LL20, 644.17/RR29, 743.08/SS2
Look out for our new paper, "Understanding the behavioural consequences of non-invasive brain stimulation", coming to you in Trends in Cognitive Sciences soon
New paper entitled "A novel coil array for combined TMS/fMRI experiments at 3T" accepted in Magnetic Resonance in Medicine